产品货号：
Z14485
中文名称：
FANCC抗体
英文名称：
Anti-FANCC Antibody
产品规格：
100μg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-FANCC Antibody |
| 指标别名 | FA3;FAC;FACC;FANCC;Fanconi anemia group C protein;Protein FACC |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | ELISA,WB |
| 基因名称 | FANCC |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | This affinity purified antibody was prepared from whole rabbit serum produced by repeated immunizations with a synthetic peptide corresponding to an internal region near amino acids 80-115 of Human FANCC. |
| 计算分子量 | 63kDa |
| 成分 | 0.02M Potassium Phosphate,0.15M Sodium Chloride,pH7.2,0.01% (w/v) Sodium Azide |
| 纯化方式 | This affinity-purified antibody is directed against human FANCC protein.The product was affinity purified from monospecific antiserum by immunoaffinity purification.A BLAST analysis was used to suggest cross-reactivity with FANCC protein from human and chimpanzee based on 100% homology with the immunizing sequence.Reactivity against homologues from other sources is not known. |
| 浓度 | 1.45mg/mL by UV absorbance at 280nm |
| 产品形态 | 溶液 |
| 保存条件 | Store vial at -20℃ prior to opening.Aliquot contents and freeze at -20℃ or below for extended storage.Avoid cycles of freezing and thawing.Centrifuge product if not completely clear after standing at room temperature.This product is stable for several weeks at 4℃ as an undiluted liquid.Dilute only prior to immediate use.Expiration date is one (1) year from date of opening. |
| 背景资料 | FANCC (also called Protein FACC or Fanconi Anemia Group C protein) is involved in DNA repair,perhaps specifically with post-replication repair or a cell cycle checkpoint function.FANCC may also be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.FANCC belongs to the multi-subunit Fanconi Anemia (FA) complex composed of FANCA,FANCB,FANCC,FANCE,FANCF,FANCG,FANCL/PHF9 and FANCM.FANCC is mainly found within the nucleus although some protein is localized in the cytoplasm.This protein is ubiquitously expressed.Defects in FANCC are a cause of Fanconi anemia (FA).FA is a genetically heterogeneous,autosomal recessive disorder characterized by cytogenetic instability,hypersensitivity to DNA crosslinking agents,increased chromosomal breakage,and defective DNA repair.The members of the Fanconi anemia complementation group do not share sequence similarity;they are related by their assembly into a common nuclear protein complex.This gene encodes the protein for complementation group C. |
| Uniprot ID | Q00597 |
| 基因名全称 | Fanconi anemia group C protein |
| 推荐稀释比 | ELISA:1:20,000 - 1:80,000 WB:1:1,000 - 1:3,000 |
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